Cell Signaling Technology

Senior Research Associate - Immunofluorescence

Job ID
Job Locations
Posted Date
3 months ago(4/6/2022 6:18 AM)
Product Development

Company Overview

About CST

Cell Signaling Technology (CST) is a private, family owned, global leader in the development and commercialization of antibodies, assays, and research tools. As a company of scientists for scientists, we have developed XMT® technology, a proprietary method to develop exceptional monoclonal antibodies, PTMScan®, a technology to discover protein post-translational modifications, and PhosphoSitePlus®, an online resource for investigation of post-translational modifications. We are passionate about our role in contributing to the life science industry’s advancing of the human condition through accelerating the discovery and development of innovative therapies for human disease.  We are fully committed to developing new research tools to help define the mechanisms underlying cell function and disease, thereby broadly accelerating progress in biomedical research and medicine.


The role

The immunofluorescence (IF) group serves as a centralized resource for the testing, analysis, optimization, and support of antibody performance in fluorescence imaging assays. We are an enthusiastic team of imaging scientists seeking a passionate, process-minded individual to help realize aggressive product release goals.


Our work is a wonderful blend of exciting science and beautiful art, and we love that! The ideal candidate should pride themselves on precise technical execution, find joy in discovery, thrive on a fun and dynamic team, and possess a creative and innovative spirit.


You'll have the opportunity to....

  • Independently perform fluorescence imaging experiments, analyze data, and communicate results to senior staff via presentation and written reports
  • Operate high-resolution microscopes, high-throughput imaging equipment, and laboratory robotics
  • Collaborate with team members to identify and refine cellular/tissue models that enable definitive characterization of antibody performance
  • Complete scientific and technical tasks on aggressive timelines, adapt to changing priorities, and manage complex and varied wet lab assignments
  • Research targets and synthesize primary literature to support or refute immunostaining results
  • Identify, analyze, and troubleshoot technical issues relating to antibody development and new lot quality assurance/quality control
  • Engage directly with customers who seek technical assistance via phone and email
  • Contribute to strategic projects that support and promote the scientific culture and values of CST
  • Proactively identify, evaluate, and champion new technologies and workflow solutions that will improve quality, efficiency, and/or scalability
  • Support our commercial organization through trainings, scientific writing, and generation of marketing collateral
  • Engage in personal and professional development activities to ensure currency of own approaches and techniques


Who you are and what you bring to the team....

  • You possess a Bachelor’s degree in a Life Sciences focus area and 4-6 years of lab experience, or a Master’s degree with 1-2 years of lab experience
  • You have first-hand experience developing and optimizing antibody-based assays
  • You are comfortable with researching, synthesizing, and reporting on topics and methods from primary literature
  • You have a conceptual understanding of western blot, flow cytometry, immunofluorescence, immunohistochemistry, and the interpretation of their results
  • You are proficient with MS Word, PowerPoint, Excel, Google Docs, and related applications
  • You possess a natural curiosity and have excellent organizational skills
  • You take initiative to complete your work in a detail-oriented manner
  • You have enthusiasm for and motivation to collaborate, and strong interpersonal skills
  • You pride yourself on being a strong communicator with excellent verbal, written, and presentation skills
  • You thrive in a team environment, while having a proven track record of completing projects independently when provided with high-level direction
  •  Ideally, you have:
    • Previous experience with confocal microscopy, spectral imaging, immunofluorescence, immunohistochemistry, and/or HTS/HCS techniques
    • Familiarity with signal transduction pathways and a broad knowledge of cellular markers
    • Practical knowledge of major organ histology and the ability to identify structures and subtypes will be evaluated
    • Working familiarity with data science tools like Python, R, or Tableau, and image analysis platforms like ImageJ and CellProfiler.


What we offer....

At Cell Signaling Technology (CST) we recognize that people will always be our most important asset. Providing a safe, inclusive, and stimulating working environment that understands the importance of diversity, human dignity and meaningful work is as important as establishing company policies that incorporate excellent health insurance and pay benefits. We recognize that development of people is the key to their happiness and thus ensure every employee has impactful discussions with their manager and develops actionable performance and professional development plans. Lastly, we are committed to engaging and supporting our employees in committees and philanthropy that benefit their local communities and environment through community investment programs.



  • Medical (BCBS) and Dental (Delta Dental) plans paid at 90%
  • Vision Insurance
  • Life Insurance, Short and Long Term Disability
  • Flexible Spending accounts
  • 401(k) Plan with 6% match
  • Tuition Reimbursement
  • Generous PTO package
  • Pet Insurance
  • Employee Assistance Program
  • Onsite Subsidized Cafeteria
  • Free Parking


Our number one priority is the health and safety of our employees, their families, our communities, partners and customers. In order to promote that safety and well-being, we require that all US-based employees be fully vaccinated against COVID-19 by their start date. Applicants who receive an offer of employment who can provide documentation that the vaccine is medically contraindicated, or who object to vaccination due to a sincerely held religious belief, may make a request for exemption. We will consider requests for reasonable accommodations consistent with our policy, and where we are able to provide such accommodations without undue hardship to the company.


Cell Signaling Technology (CST) is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, status as a veteran or as a member of the military or status in any group protected by applicable federal or state laws.



All resumes submitted by search firms/employment agencies to any employee at Cell Signaling Technology (CST) via email, the internet or in any form and/or method will be deemed the sole property of CST, unless such search firms/employment agencies were engaged by CST for this position and a valid agreement with CST is in place. In the event a candidate who was submitted outside of the CST agency engagement process is hired, no fee or payment of any kind will be paid.


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