Cell Signaling Technology

Research Associate - Contract

Job Locations US-MA-Danvers
Posted Date 2 weeks ago(3/20/2020 9:28 AM)
Job ID
Product Development

Company Overview

Cell Signaling Technology, Inc. (CST) is a worldwide leader in the development and commercialization of antibodies, assays and research tools. As a company of scientists for scientists, we have developed PTMScan®, a technology to discover protein post-translational modifications, P hosphoSitePlus®, an online resource for investigation of post-translational modifications, and XMT® technology, a proprietary method to develop exceptional monoclonal antibodies. We are fully committed to developing new research tools to help define the mechanisms underlying cell function and disease, thereby broadly accelerating progress in biomedical research and medicine.

Position Summary

We are seeking a Contract Research Associate to join our Antibody Development Core, a highly dynamic and diverse group whose mission is to identify and characterize antibodies for application testing by internal development scientists. The Molecular Biology group within our Antibody Development Core specifically serves as a centralized resource for recombinant DNA cloning, Sanger sequencing, and plasmid preparation.


We are seeking a Research Associate with experience in basic Molecular Biology techniques. This individual will be responsible for delivering high quality plasmid DNA to serve our in-house antibody validation and production needs, in a timely and efficient manner.


  • Produce recombinant antibody and protein expression constructs through transformation of E. Coli and Qiagen plasmid preparations (both manual and automated protocols)
  • Perform quality control experiments (quantification using QIAxpert, Sanger sequencing reactions) and proper labeling/delivery of plasmid materials to internal customers
  • Organize plasmid master stock materials and maintain inventory of related reagents and supplies
  • Maintain accurate and complete product development laboratory documentation (both hard copy laboratory notebooks and electronic, e.g. JIRA, CoreLIMS, Google Drive, PDP, etc.)


  • Bachelor’s degree in a biological science or related degree (e.g. molecular biology, cell biology, biochemistry or biotechnology)
  • 1+ years of laboratory experience
  • Experience with Microsoft Excel



Preferred Skills/Experience

  • Previous hands on experience with general molecular biology techniques (e.g. PCR, plasmid purification, DNA cloning, Sanger DNA sequencing, etc.)
  • Ability to analyze data and troubleshoot experimental problems
  • Previous experience working with automated liquid handlers
  • Prior knowledge and experience with a laboratory information management system (LIMS)
  • Strong detail orientation and organizational skills
  • Proven ability to work in a high-throughput and fast-paced environment
  • Strong oral and written communication skills
  • Proven experience working successfully in a team environment



Cell Signaling Technology, Inc. is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, status as a veteran or as a member of the military or status in any group protected by applicable federal or state laws.


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