• Research Associate - Chromatin IP (ChIP)

    Job Locations US-MA-Danvers
    Posted Date 1 month ago(10/1/2019 12:49 PM)
    Job ID
  • Position Summary


    Cell Signaling Technology, Inc. (CST) is a worldwide leader in the development and commercialization of antibodies, assays and research tools. As a company of scientists for scientists, we have developed PTMScan®, a technology to discover protein post-translational modifications, PhosphoSitePlus®, an online resource for investigation of post-translational modifications, and XMT® technology, a proprietary method to develop exceptional monoclonal antibodies. We are fully committed to developing new research tools to help define the mechanisms underlying cell function and disease, thereby broadly accelerating progress in biomedical research and medicine.


    We are currently seeking a highly motivated Research Associate to join a team dedicated to the development of epigenetics-based assays. The candidate will contribute to the development of innovative research tools, with a primary focus on antibody validation and assay development for chromatin IP (ChIP), ChIP-Seq and related technologies. Major lab techniques include chromatin preparation, ChIP, DNA purification, PCR, DNA sequencing library preparation and cell culture. Applicants must be able to design moderately complex experiments with proper controls and are expected to independently interpret and report results.


    • Collaborate with senior project scientists and other research associates to manage a fast-paced pipeline and complete scientific tasks on aggressive timelines to support internal and external customers
    • Independently test antibody and reagent performance in chromatin IP (ChIP) and related assays; techniques include cell culture, chromatin preparation, chromatin IP, DNA purification, qPCR, and DNA sequencing library preparation
    • Analyze experimental data and communicate results to senior project scientists via presentation and email
    • Identify, analyze and troubleshoot technical issues relating to antibody and reagent performance in the ChIP assay
    • Collaborate with senior project scientists to identify, develop, and release new protocols and products to support ChIP and related workflows
    • Provide support to colleagues in the commercial organization by reviewing datasheets and technical literature, generating scientific content for webinars and other marketing collateral


    Required Skills/Experience:

    • BA/BS, or MS degree in a biological science (e.g. Molecular Biology, Cell Biology, Biochemistry or Biotechnology)
    • 1+ year's laboratory experience
    • Hands-on experience with cell culture, PCR and immunoprecipitation

    Preferred Skills/Experience:

    • Experience with ChIP assay is a plus
    • Strong organizational skills and attention to detail
    • Ability to work independently with a collaborative mindset
    • Ability to multi-task effectively and manage multiple priorities at one time
    • Strong verbal and written communication skills and ability to thrive in a team environment
    • Familiarity with computer programs such as Microsoft Word, Excel and PowerPoint

    Cell Signaling Technology, Inc. is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, status as a veteran or as a member of the military or status in any group protected by applicable federal or state laws.


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