Cell Signaling Technology

  • Research Associate - IHC

    Job Locations US-MA-Danvers
    Posted Date 1 month ago(11/13/2018 12:37 PM)
    Job ID
    Product Development
  • Company Overview

    Cell Signaling Technology, Inc. (CST) is a worldwide leader in the development and commercialization of antibodies, assays and research tools. As a company of scientists for scientists, we have developed PTMScan®, a technology to discover protein post-translational modifications, P hosphoSitePlus®, an online resource for investigation of post-translational modifications, and XMT® technology, a proprietary method to develop exceptional monoclonal antibodies. We are fully committed to developing new research tools to help define the mechanisms underlying cell function and disease, thereby broadly accelerating progress in biomedical research and medicine.

    Position Summary

    We are seeking a Research Associate to join our highly collaborative, fast-paced, Immunohistochemistry team.  The mission of the Immuohistochemistry Group is to serve as a core provider of immunohistochemical analysis of cells and tissues in support of the Product Development and Production. Team members are responsible for delivery of thorough, high quality paraffin-embedded cell pellets and tissues within established service level agreements and continued monitoring of processes in order to reduce testing times.


    • Culture and treat mammalian cell lines to prepare high quality paraffin-embedded cell pellets in support of IHC testing
    • Conduct scientific experiments, including western blots to verify efficacy of cell treatments
    • Prepare paraffin-embedded animal tissues, syngeneic tumors and xenografts in conjunction with the Animal Facility staff
    • Maintain the inventory of paraffin-embedded human tissues, including sample logging and management of associated clinical data, when applicable
    • Support the execution of IHC testing
    • Maintain tissue processing and embedding equipment per established policies
    • Maintain accurate and complete hard copy and electronic laboratory documentation in appropriate systems including capturing data in testing databases in accordance with quality systems requirements
    • Develop an understanding of the antibody development process and maintaining an awareness of such as changes are implemented
    • Understand and follow established protocols for all established group processes and procedures as detailed in SOPs and training documents
    • Seek opportunities that will improve quality, efficiency, or scalability of cell culture and other group processes
    • Adhere to safety procedures in and around the laboratory


    • Bachelors degree in a biological science (e.g. molecular biology, cell biology, biochemistry or biotechnology)
    • Basic hands on laboratory experience through academic exposure, internship or work experience

    Preferred Skills/Experience:

    • 1-2 years previous laboratory experience preferred
    • Previous experience with tissue culture
    • Multi tasking with effective management of multiple, changing priorities
    • Strong organizational skills
    • Attention to detail
    • Strong verbal and written communication skills
    • Highly dependable and team-focused


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